Dogs Lead Way in Arthritis Research

1 decade 1 year 10 months ago Wednesday, July 12 2006 Jul 12, 2006 Wednesday, July 12, 2006 6:37:15 PM CDT July 12, 2006 in News

And, it's easier to use dogs as test subjects because they devleop arthritis faster than people. Cook has found genetic signs for arthritis, genes that can increase the likelihood of developing the disease as well as providing a possible breakthrough in prevention.

"There are indicators that aren't that specific right now, you know, that says what the liklihood is of your getting arthritis," he said. "But, what we want is very specific ones that are 95%-plus accurate."

Cook and research partner Aaron Stoker induced arthritis in test dogs, then looked at signs and indicators that appeared as the disease became worse.

"If we identify which genes and which proteins are the most problematic, then we can direct therapies towards those," said Cook.

There is no routine screening for arthritis, and techniques often are inconclusive. Cook hopes his research will make testing as routine as prostate exams or mammograms. To prevent arthritis, doctors recommend keeping fit and active, and having a joint exam when you reach 40 years old.

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