LONDON (AP) — Pfizer and BioNTech have submitted a request to the European drug regulator for the approval of their coronavirus vaccine to be extended to include children aged 12 to 15 years old, in a move that could offer younger and less at-risk populations in Europe access to the shot for the first time.

The two pharmaceuticals said their submission to the European Medicines Agency is based on an advanced study in more than 2,000 adolescents that showed their vaccine to be safe and effective.

The COVID-19 vaccine made by Pfizer and BioNTech was the first one to be granted a greenlight by the EMA last December.

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