Governor Blunt declared a state of emergency and authorized Missouri National Guard troops to be mobilized.
A spokeswoman for the State Emergency Management Agency says emergency shelters are set up in St. Joseph and Mound City. She says evacuations are under way in some towns in Atchison, Holt, Jackson, Clay, Platte, Andrew and Daviess counties.
The water is expected to rise steadily over the next four days.
The national weather service predicts the Missouri river will crest at 34 feet by Friday evening, 13 feet above flood stage.
In mid-Missouri the Boone County fire protection district and Columbia Boone County office of emergency management needs volunteers to sandbag.
Sand bagging efforts will start at 1p.m. in Rocehport and move south toward Huntsdale, McBaine and Hartsburg.
The fire districts says volunteers should be physically fit and capable of performing strenuous work and able to lift 50 pounds.
Volunteers should report to the Boone County Fire Protection district Station 2 at 104 Central Street in Rocheport at 1p.m.
KOMU has reporters in the field and will have details on how the flood will impact Mid-Missouri.
Stay tuned to KOMU.com and KOMU News for details on potential flooding.