MU Researchers hit "milestone" that could help treat cancer

3 months 4 days 1 hour ago Tuesday, August 14 2018 Aug 14, 2018 Tuesday, August 14, 2018 6:57:00 PM CDT August 14, 2018 in News
By: Alayna Chapie, KOMU 8 Reporter
loading

COLUMBIA - MU researchers say they've hit a "milestone" in developing a cancer treatment that could be more effective than traditional chemotherapy.

Molecular biophysicist David Porciani said one of the issues with chemotherapy is that it can kill all cells, not just the bad ones. 

"The idea is to develop some new smart molecules that can discriminate between the tumor cells and the healthy cells," he said. 

Porciani said the concept isn't something knew. In the early 1900 century, Paul Ehrlich came up with the concept of the "magic bullet." 

"This bullet is able to avoid any innocents and just kill the guilty person, for example. In this case, the innocents are the healthy cells and the guilty person is the disease cell, the tumor cell," he said.

In their most recent publication, MU researchers said they were able to use smart molecules to recognize a particular protein and thus lock onto only unhealthy cells.

The next goal is to insert therapeutic molecules that will only target cancer cells. The team has been able to test the effectiveness of their treatment by using fluorescent substances.

"In our work, we deliver something that can allow the cell to glow and the RNA itself is glowing. And the current effort are based to replace this glowing RNA with therapeutic RNAs," Porciani said. 

The principal investigator for the research group said it took the study to the next level.

"In this case, by attaching a much larger cargo than others have used before," Donald Burke-Aguero said.

He said he thinks his team is the only group trying to deliver large RNA molecule cargo to the tumor cells. 

Porciani said there is never an end to cancer research because there are always more questions. 

He believes it could be many years before the treatment is ready for human trials.

More News

Grid
List
BOONE COUNTY - One person was hospitalized Saturday evening after a shooting just east of Columbia, the Boone County Sheriff's... More >>
3 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 11:01:00 PM CST November 17, 2018 in News
LAKE OZARK - Community members gathered Saturday to raise money for the Police Unity Tour. Every year, police officers... More >>
7 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 7:12:00 PM CST November 17, 2018 in News
COLUMBIA - A Columbia man is home from the hospital Saturday after spending three weeks in the ICU, recovering from... More >>
7 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 6:58:00 PM CST November 17, 2018 in News
PHELPS COUNTY - One man was airlifted to the hospital Saturday morning after he suffered "a large caliber gunshot wound... More >>
9 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 4:46:00 PM CST November 17, 2018 in News
COLUMBIA - Fall Into Art kicked off the weekend with its annual show, and artists shared what their art means... More >>
10 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 3:50:00 PM CST November 17, 2018 in News
COLUMBIA - One of the largest holiday shopping events in mid-Missouri takes place Saturday and Sunday at the Columbia Exposition... More >>
12 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 2:20:00 PM CST November 17, 2018 in News
COLUMBIA - From the amateurs to the professional travel teams, dodgeball players of all skill sets took part in the... More >>
12 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 2:05:00 PM CST November 17, 2018 in News
CALLAWAY COUNTY - A chase that reached speeds of 115 mph and a subsequent foot pursuit led to the arrest... More >>
13 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 12:50:00 PM CST November 17, 2018 in News
Royal Palm Beach, FL ( WPTV ) -- Firefighters rescued several pets from a house fire in Royal Palm Beach... More >>
15 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 11:45:00 AM CST November 17, 2018 in News
COLE COUNTY - Another fatal crash occurred in Missouri early Saturday morning. 30 year-old Richard Lowry, of Eugene, was pronounced... More >>
20 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 5:57:00 AM CST November 17, 2018 in News
SEDALIA - A Sedalia woman was pronounced dead following a crash near Sedalia on Nov. 16. 51-year-old Janna McQueen... More >>
21 hours ago Saturday, November 17 2018 Nov 17, 2018 Saturday, November 17, 2018 5:24:00 AM CST November 17, 2018 in News
SPRINGFIELD (AP) — A jury has found a Wisconsin man guilty of first-degree murder for killing a Missouri mother who... More >>
1 day ago Friday, November 16 2018 Nov 16, 2018 Friday, November 16, 2018 9:47:00 PM CST November 16, 2018 in News
COLUMBIA - Families filled empty shoeboxes with hygiene products, school supplies, clothes, shoes and toys for children in need at... More >>
1 day ago Friday, November 16 2018 Nov 16, 2018 Friday, November 16, 2018 8:04:00 PM CST November 16, 2018 in News
COLUMBIA - The price of a typical Thanksgiving meal in Missouri is a full $5.25 higher than the national average.... More >>
1 day ago Friday, November 16 2018 Nov 16, 2018 Friday, November 16, 2018 7:18:00 PM CST November 16, 2018 in News
JEFFERSON CITY - The nature of Twitter and how government officials use it was at the heart of a hearing... More >>
1 day ago Friday, November 16 2018 Nov 16, 2018 Friday, November 16, 2018 4:11:00 PM CST November 16, 2018 in News
ST. LOUIS - The University of Missouri Board of Curators announced cuts to costs Friday to help with enrollment at... More >>
1 day ago Friday, November 16 2018 Nov 16, 2018 Friday, November 16, 2018 3:24:00 PM CST November 16, 2018 in News
(CNN) -- USA Gymnastics' longtime chief operating officer has resigned, the organization said Friday, becoming the latest in a string... More >>
1 day ago Friday, November 16 2018 Nov 16, 2018 Friday, November 16, 2018 2:56:27 PM CST November 16, 2018 in News
COLUMBIA- A tree in downtown Columbia became the target of vandalism Thursday night when two men were caught on camera... More >>
1 day ago Friday, November 16 2018 Nov 16, 2018 Friday, November 16, 2018 2:49:00 PM CST November 16, 2018 in News
Columbia, MO
Broken Clouds 34°
3am 32°
4am 31°
5am 31°
6am 31°