MU Researchers hit "milestone" that could help treat cancer

1 year 11 months 3 weeks ago Tuesday, August 14 2018 Aug 14, 2018 Tuesday, August 14, 2018 6:57:00 PM CDT August 14, 2018 in News
By: Alayna Chapie, KOMU 8 Reporter
loading

COLUMBIA - MU researchers say they've hit a "milestone" in developing a cancer treatment that could be more effective than traditional chemotherapy.

Molecular biophysicist David Porciani said one of the issues with chemotherapy is that it can kill all cells, not just the bad ones. 

"The idea is to develop some new smart molecules that can discriminate between the tumor cells and the healthy cells," he said. 

Porciani said the concept isn't something knew. In the early 1900 century, Paul Ehrlich came up with the concept of the "magic bullet." 

"This bullet is able to avoid any innocents and just kill the guilty person, for example. In this case, the innocents are the healthy cells and the guilty person is the disease cell, the tumor cell," he said.

In their most recent publication, MU researchers said they were able to use smart molecules to recognize a particular protein and thus lock onto only unhealthy cells.

The next goal is to insert therapeutic molecules that will only target cancer cells. The team has been able to test the effectiveness of their treatment by using fluorescent substances.

"In our work, we deliver something that can allow the cell to glow and the RNA itself is glowing. And the current effort are based to replace this glowing RNA with therapeutic RNAs," Porciani said. 

The principal investigator for the research group said it took the study to the next level.

"In this case, by attaching a much larger cargo than others have used before," Donald Burke-Aguero said.

He said he thinks his team is the only group trying to deliver large RNA molecule cargo to the tumor cells. 

Porciani said there is never an end to cancer research because there are always more questions. 

He believes it could be many years before the treatment is ready for human trials.

More News

Grid
List
Not only is there a global pandemic in the year 2020, we’ve also been dealing with a very active start... More >>
2 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 8:27:00 PM CDT August 06, 2020 in Weather
COLUMBIA - With just over two weeks until Mizzou's fall semester begins, KOMU 8's Emily Spain talked with MU Health... More >>
4 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 6:57:00 PM CDT August 06, 2020 in News
COLUMBIA — The City of Columbia will host a virtual information meeting Thursday at 7:30 p.m. to discuss new loan... More >>
5 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 6:03:00 PM CDT August 06, 2020 in News
MISSOURI — As COVID-19 continues to spread throughout Missouri, state and local officials confirm new case counts daily. This... More >>
5 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 5:30:00 PM CDT August 06, 2020 in News
COLUMBIA — Columbia/Boone County Public Health and Human Services director Stephanie Browning issued a new health order on Thursday. ... More >>
6 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 4:47:00 PM CDT August 06, 2020 in News
COLUMBIA — State and federal governments announced steps aimed at reining in violent crime in St. Louis Thursday, prompting... More >>
6 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 4:42:09 PM CDT August 06, 2020 in News
MISSOURI — Back to school shopping? This weekend, sales tax won't apply. From Friday through Sunday, certain back to... More >>
7 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 3:52:22 PM CDT August 06, 2020 in News
COLUMBIA - Missourians voted on Tuesday to pass Amendment 2, expanding Medicaid eligibility throughout the state. Joshua Dunne, chair... More >>
7 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 3:52:00 PM CDT August 06, 2020 in News
COLUMBIA - When COVID-19 began to shutdown mid-Missouri in March, many wondered how long the pandemic would last. Some... More >>
8 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 2:32:00 PM CDT August 06, 2020 in News
COLUMBIA — Missourians who qualify under the newly expanded Medicaid qualifications will have to wait almost a year to... More >>
8 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 2:28:00 PM CDT August 06, 2020 in News
As COVID-19 continues to spread, KOMU 8 will continue to update you about impacts in the community. You can... More >>
9 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 2:13:00 PM CDT August 06, 2020 in News
WASHINGTON — Sen. Josh Hawley's bill to ban TikTok on government devices passed the U.S. Senate unanimously on Thursday, according... More >>
10 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 12:51:00 PM CDT August 06, 2020 in News
JEFFERSON CITY —Four people have tested positive for COVID-19 following open testing at the Missouri Capitol. The state health... More >>
11 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 12:23:50 PM CDT August 06, 2020 in News
(CNN) -- Former First Lady Michelle Obama says she's suffering from a "low-grade depression." The reasons? The pandemic, race relations... More >>
12 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 10:53:16 AM CDT August 06, 2020 in A Brighter Tomorrow
At the beginning of the Coronavirus pandemic, NBC news reported people with eating disorders were suffering due to social isolation.... More >>
12 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 10:41:00 AM CDT August 06, 2020 in A Brighter Tomorrow
LAKE OF THE OZARKS - An Illinois man was killed on the Lake of the Ozarks Sunday after a boating... More >>
14 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 9:07:00 AM CDT August 06, 2020 in News
HARTSBURG - The 2020 Hartsburg Pumpkin Festival will be canceled due to the COVID-19 pandemic. The festival was set to... More >>
14 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 8:56:00 AM CDT August 06, 2020 in News
BOONVILLE - A Boonville man pleaded guilty to child molestation Wednesday and was given 5 years probation. A grand... More >>
14 hours ago Thursday, August 06 2020 Aug 6, 2020 Thursday, August 06, 2020 8:32:38 AM CDT August 06, 2020 in News
Columbia, MO
Broken Clouds 70°
12am 70°
1am 70°
2am 69°
3am 69°