MU researchers to use pigs to study treatment for diabetic blindness

5 months 3 weeks 5 days ago Wednesday, April 25 2018 Apr 25, 2018 Wednesday, April 25, 2018 7:27:00 PM CDT April 25, 2018 in News
By: Joshua Tyler, KOMU 8 Reporter
loading

COLUMBIA - MU researchers say there will be 600 million people with some level of diabetic blindness by the year 2040. 

Diabetic retinopathy is a retinal disease that often cause blindness in adults for 10 or more years.

But researchers say they have found the protein that causes the disease.

"We found a protein complex called NLRP3 has played a very important role in the progression of the disease," Dr. Shyam Chaurasia, who led the research team. "If you can find a drug which can block or not allow this protein to be expressed, we can actually stop the progression of the disease."

The protein causes vessels in the person's eyes to start leaking. If the leakage goes untreated, it will cause complete blindness. Currently, the disease can only be discovered in humans when it has already caused some level of blindness. 

Chaurasia said they have also discovered similar features of diabetic retinopathy in Ossabaw pigs. They will use the pigs as a model to study various treatments and other mechanisms of the disease. 

"We can create these animal models and genetically manipulate to see their functionality, as well as similarity to the human eyes and how we can see the progression of the disease in these pigs," he said. 

Ossabaw pigs are special because they are born with type-2 diabetes and develop diabetic retinopathy without manipulation, according to Chaurasia. 

Chaurasia said the best way for diabetics to avoid potential issues is to manage and control high sugar intake. 

More News

Grid
List
(CNN) - The Washington Post says Saudi Arabia's announcement about the death of contributing columnist Jamal Khashoggi is not an... More >>
1 hour ago Sunday, October 21 2018 Oct 21, 2018 Sunday, October 21, 2018 2:28:00 PM CDT October 21, 2018 in News
COLE COUNTY - One man is dead after being ejected from his motorcycle during a crash Saturday night. Kin... More >>
6 hours ago Sunday, October 21 2018 Oct 21, 2018 Sunday, October 21, 2018 9:15:00 AM CDT October 21, 2018 in News
PECULIAR - Fourth generation dairy farmer Jay Fogle is one of many Missouri milk cow operators who are struggling to... More >>
7 hours ago Sunday, October 21 2018 Oct 21, 2018 Sunday, October 21, 2018 8:45:00 AM CDT October 21, 2018 in News
COLUMBIA - One person was killed in a crash late Saturday night on North Stadium Boulevard (State Route E) near... More >>
15 hours ago Sunday, October 21 2018 Oct 21, 2018 Sunday, October 21, 2018 12:47:00 AM CDT October 21, 2018 in News
HERMANN - One person was killed and several people were injured in a crash involving a trolley, according to the... More >>
16 hours ago Saturday, October 20 2018 Oct 20, 2018 Saturday, October 20, 2018 11:57:00 PM CDT October 20, 2018 in News
(CNN) -- President Donald Trump announced Saturday that the US is pulling out of the landmark Intermediate-Range Nuclear Forces Treaty... More >>
22 hours ago Saturday, October 20 2018 Oct 20, 2018 Saturday, October 20, 2018 5:11:00 PM CDT October 20, 2018 in News
COLUMBIA – Nineteen members of Missouri Task Force One returned to Boone County Fire Protection District headquarters Saturday morning after... More >>
1 day ago Saturday, October 20 2018 Oct 20, 2018 Saturday, October 20, 2018 3:16:00 PM CDT October 20, 2018 in News
SPRINGFIELD (AP) — A man has been criminally charged days after a woman's body was found near Fellows Lake at... More >>
1 day ago Saturday, October 20 2018 Oct 20, 2018 Saturday, October 20, 2018 1:58:08 PM CDT October 20, 2018 in News
SPRINGFIELD (AP) — A Springfield woman who killed her live-in boyfriend with a crowbar in 2017 has been sentenced to... More >>
1 day ago Saturday, October 20 2018 Oct 20, 2018 Saturday, October 20, 2018 1:48:36 PM CDT October 20, 2018 in News
ST. LOUIS (AP) — A restored St. Louis prairie of native grasses and flowers is in bloom, but the nature... More >>
1 day ago Saturday, October 20 2018 Oct 20, 2018 Saturday, October 20, 2018 8:50:24 AM CDT October 20, 2018 in News
COLUMBIA - Sen. Claire McCaskill spoke about health care in Columbia on Friday at Laborers Local 955, as part of... More >>
1 day ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 7:35:00 PM CDT October 19, 2018 in News
COLUMBIA - After realizing the underrepresentation of Hispanic business owners in mid-Missouri, three Hispanic professionals established a group of 12... More >>
1 day ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 5:49:00 PM CDT October 19, 2018 in News
COLUMBIA - This is the last week of the regular season and it's a cold one. Our game of... More >>
1 day ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 5:20:00 PM CDT October 19, 2018 in Friday Night Fever
COLUMBIA - Two Midwest companies issued separate food recalls this week for bacterial contamination concerns. Hy-Vee said its supplier,... More >>
1 day ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 4:53:00 PM CDT October 19, 2018 in News
CAMDEN (AP) — Toxicology tests show that a boater was drunk when he slammed into a bluff at Missouri's Lake... More >>
2 days ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 3:41:35 PM CDT October 19, 2018 in News
COLUMBIA - The Legion of Black Collegians and the FourFront Marginalized Student Council held a solidarity walk Friday to show... More >>
2 days ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 3:39:00 PM CDT October 19, 2018 in News
JEFFERSON CITY - The Missouri State Medical Association (MSMA), along with multiple medical associations, reaffirmed their opposition to the three... More >>
2 days ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 2:50:00 PM CDT October 19, 2018 in News
JEFFERSON CITY - For the fourth consecutive year, Project Homeless Connect provided services Friday for people who are experiencing homelessness... More >>
2 days ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 2:39:00 PM CDT October 19, 2018 in News
Columbia, MO
Broken Clouds 57°
4pm 58°
5pm 57°
6pm 55°
7pm 53°