New preservation method doubles life for donor tissues

3 years 6 months 2 weeks ago Sunday, April 05 2015 Apr 5, 2015 Sunday, April 05, 2015 6:37:00 PM CDT April 05, 2015 in News
By: Phil Bergman, KOMU 8 Reporter
loading

COLUMBIA - MU researchers have created new technology to help double the life of certain donor tissue, making it easier for patients to come in and get joint surgery done at their own convenience.

Currently, patients have two options when getting joint surgery done. The first uses metal and plastic implants. Though stable, these implants often force patients to stop doing many of their previous activities and sometimes can make it so they can't be up to full athletic capacity again.

The second option uses bone and cartilage grafts from organ donors, which remain stable for an extended time. This is problematic, however, because of the life expectancy of donated cartilage. It is good for only 28 days from the time of donation, which means more than 80 percent is thrown away before it can be used in surgery. Donated cartilage must be refrigerated. 

"Cartilage, like me, doesn't like to be cold," said Dr. James Stannard, medical director of the Missouri Orthopedic institute. "And so, it tends to not do well."

Stannard saif the cartilage has to come from a donor of a similar size to the patient. Sometimes, a patient will get a call saying there's a match and will be in surgery three days later. This puts a strain on many of the patient's lives and makes it hard for them to know when they need to take off work and other important scheduling issues.

However, with the new technology created by MU researchers, all of these problems may be alleviated. The new technology, called the Missouri Osteochondral Allograft Preservation System (MOPS), doubles the life span of the cartilage from 28 days to 60 days.

"With the new technology we have about an 85 percent success rate of the grafts living and that's good but not great. We would like 95 percent," Stannard said. "I'm hoping, by putting in grafts with way more live cells at the time we put them in, that we will move that success rate way up."

The new system keeps cartilage in little jars with a special solution at room temperature, which both extends the life span of the tissue and makes it so the cartilage is easier to use in surgery. Most importantly, the doubling of the life span makes it so patients don't need to drop everything at the last second to get the surgery done.

For Dr. Dusty Nagy, a large animal veterinarian at the MU College of Medicine, this would have been extremely helpful.

"When I got my surgery, it was 'we have a suitable sample for you and we need you in surgery next week,'" Nagy said. "We run a three-service practice training veterinary students and so not knowing when they had to accommodate when I was going to be two months out was very difficult."

For Nagy's job, movement is critical and an injury she received while playing basketball in 1992 has affected her.

"I spend a lot of time on my knees, jumping, running and sometimes running as a lifesaving methodology," she said. "I need to be able to run jump and climb and I need to be able to trust the leg." 

Since the surgery, which used the 28-day cartilage, Nagy has seen a big change in her mobility, which she also said used to impact what her family can do.

"The knee has been fantastic. I absolutely love it," Nagy said. "I'm pain-free. The knee doesn't hurt at all, I have almost full mobility and it has not slowed me down at work which is fantastic."

While the 60-day cartilage has not been used yet on humans, Stannard said he hopes to soon and thinks the new preservation system could have a huge impact in the field on orthopedic surgery.

"I just really think this could potentially be a game changer where we restore a lot of patients that otherwise were looking at a life of disability and some degree of crippling pain to very close to their normal self."

 

More News

Grid
List
COLUMBIA - This is the last week of the regular season and it's a cold one! Our game of... More >>
1 hour ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 5:20:00 PM CDT October 19, 2018 in Friday Night Fever
COLUMBIA - Two Midwest companies issued separate food recalls this week for bacterial contamination concerns. Hy-Vee said its supplier,... More >>
1 hour ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 4:53:00 PM CDT October 19, 2018 in News
CAMDEN (AP) — Toxicology tests show that a boater was drunk when he slammed into a bluff at Missouri's Lake... More >>
2 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 3:41:35 PM CDT October 19, 2018 in News
JEFFERSON CITY - The Missouri State Medical Association (MSMA), along with multiple medical associations, reaffirmed their opposition to the three... More >>
3 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 2:50:00 PM CDT October 19, 2018 in News
JEFFERSON CITY - For the fourth consecutive year, Project Homeless Connect provided services Friday for people who are experiencing homelessness... More >>
3 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 2:39:00 PM CDT October 19, 2018 in News
DES MOINES, Iowa (AP) — The Mega Millions jackpot has soared to an estimated $1 billion, as the second-largest lottery... More >>
6 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 12:10:00 PM CDT October 19, 2018 in News
JEFFERSON CITY - Police want the public's help finding a man who allegedly ran from a traffic stop after hurting... More >>
6 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 11:42:00 AM CDT October 19, 2018 in News
COLUMBIA - Two MU residence halls and an atrium were officially dedicated on Friday honoring three former MU students. Lucile... More >>
8 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 10:09:00 AM CDT October 19, 2018 in News
WASHINGTON (AP) — Just 1 in 4 people thinks Brett Kavanaugh was completely honest when as a Supreme Court nominee... More >>
8 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 9:58:13 AM CDT October 19, 2018 in News
(CNN) -- The US moved closer to acknowledging the role of Saudi Arabia in journalist Jamal Khashoggi's apparent death as... More >>
9 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 9:36:16 AM CDT October 19, 2018 in News
RANDOLPH COUNTY - MoDOT announced they will close Randolph County Route CC from Route FF to Route K on Monday,... More >>
10 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 8:30:00 AM CDT October 19, 2018 in News
FLORISSANT (AP) — Authorities have arrested a suburban St. Louis student after finding a loaded gun and a razor inside... More >>
10 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 7:46:15 AM CDT October 19, 2018 in News
ST. CHARLES, Mo. (AP) — A Missouri man has been sentenced to life in prison in the 1984 beating death... More >>
11 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 7:10:00 AM CDT October 19, 2018 in News
KANSAS CITY, Mo. (AP) — A Kansas City doctor has been sentenced to a year in federal prison for his... More >>
11 hours ago Friday, October 19 2018 Oct 19, 2018 Friday, October 19, 2018 6:51:00 AM CDT October 19, 2018 in News
ST. LOUIS - Democratic Sen. Claire McCaskill and Republican opponent Josh Hawley were sometimes heated and often derisive as they... More >>
21 hours ago Thursday, October 18 2018 Oct 18, 2018 Thursday, October 18, 2018 9:02:00 PM CDT October 18, 2018 in News
COLUMBIA - After realizing the underrepresentation of Hispanic business owners in mid-Missouri, three Hispanic professionals established a group of 12... More >>
22 hours ago Thursday, October 18 2018 Oct 18, 2018 Thursday, October 18, 2018 8:16:00 PM CDT October 18, 2018 in News
COLUMBIA - Issues like Proposition D, Vision Zero and more were discussed at Thursday night's Transportation Committee Meeting in Columbia.... More >>
23 hours ago Thursday, October 18 2018 Oct 18, 2018 Thursday, October 18, 2018 7:31:00 PM CDT October 18, 2018 in News
MEXICO - October is domestic violence awareness month and businesses across Mexico are showing their support for survivors by decorating... More >>
1 day ago Thursday, October 18 2018 Oct 18, 2018 Thursday, October 18, 2018 6:02:00 PM CDT October 18, 2018 in News
Columbia, MO
Broken Clouds 57°
7pm 57°
8pm 57°
9pm 55°
10pm 55°